| 货号:RQ7227 | 规格:100 ug | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD135 Antibody / FLT3
产品描述:
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, Direct ELISA
同种型:
Rabbit IgG
免疫原:
Recombinant human protein (amino acids A66-S993) was used as the immunogen for the CD135 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the CD135 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
上一个:EIF3A Antibody / Eukaryotic translation initiation factor 3 subunit A
下一个:HAVCR2 Antibody / TIM-3
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