CD27 (human) (rec.) (His)-其他重组蛋白-深圳欣博盛生物科技有限公司

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CD27 (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HR-200CD27-C050

规格：50 ug

目录价：￥4480

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD27 (human) (rec.) (His)

别名:

T Cell Activation Antigen CD27; T14; TNFRSF7; Tumor Necrosis Factor Receptor Superfamily Member 7; S152

产品描述:

CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B cell differentiation, activation and immunoglobulin synthesis. The CD27 receptor transduces signals and subsequently leads to the activation of NF-kappaB and MAPK8/JNK, mediated by the adaptor proteins TRAF2 and TRAF5. In addition, the proapoptotic protein SIVA is capable of binding the cytoplasmic tail of CD27 and exerts action in the process of apoptosis.

宿主来源:

E. coli

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in 50mM Tris-HCl buffer (pH 8.0) and 500mM NaCl.

产地:

瑞士

纯度: