| 货号:ANC-541-820 | 规格:25 ug | 目录价:¥6244 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD274 [B7-H1/PD-L1] (human)-muIg Fusion Protein (preservative free)
别名:
B7-H1; Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1
产品描述:
CD274 (B7-H1; PD-L1; Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation and is involved in progression of cancer, arthritis and HIV infection. CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in renal cell carcinoma is associated with poor prognosis. Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival.
宿主来源:
CHO cells
偶联:
Preservative Free
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
产地:
瑞士
上一个:CD274 [B7-H1/PD-L1] (human)-muIg Fusion Protein (Biotin)
下一个:CD272 [BTLA] (human)-muIg Fusion Protein
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