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折扣/货期| 货号：ANC-505-820 | 规格：25 ug | 目录价：￥6244 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD40L [CD154] (human)-muCD8 Fusion Protein (preservative free)
产品描述:
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. It can undergo proteolytic cleavage into a 19kDa immunologically active soluble form. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. Increased levels of CD154 has been associated with autoimmune disorders including SLE, CLL and eosinophilic fasciitis. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells, macrophages and activated platelets indicating a role for the CD40-CD154 immunoregulatory signaling in artherosclerosis and cardiovascular disorders.
宿主来源:
CHO cells
偶联:
Preservative Free
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
产地:
瑞士
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