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折扣/货期| 货号：41099-10 mg | 规格：10 mg | 目录价：￥1903 |
| 货号：41099-25 mg | 规格：25 mg | 目录价：￥4516 |
| 货号：41099-5 mg | 规格：5 mg | 目录价：￥1005 |
| 货号：41099-50 mg | 规格：50 mg | 目录价：￥8027 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CDKI-73
别名:
Asnuciclib
产品描述:
An inhibitor of Cdk9/cyclin T1, Cdk1/cyclin B, and Cdk2/cyclin A complexes (Kis = 4, 4, and 3 nM, respectively); selective for these complexes over the Cdk7/cyclin H complex (Ki = 91 nM); cytotoxic to HCT116 cells (GI50 = <10 nM); induces apoptosis in COLO 205, HCT116, HT-29, and KM12 cells at 0.25 or 1 µM; reduces the levels of Bcl-2, cyclin D1, and Mcl-1, as well as decreases the mitochondrial membrane potential, in HCT116 cells at 0.25 µM; decreases tumor volume in an HCT116 mouse xenograft model at 100 mg/kg every three days
保存温度:
-20
运输温度:
-20
预期分子量:
394.449243
产品形式:
A solid
纯度:
≥98%
CAS号:
1421693-22-2
分子式:
C15H15FN6O2S2
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