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折扣/货期| 货号：29665-10 mg | 规格：10 mg | 目录价：￥1997 |
| 货号：29665-25 mg | 规格：25 mg | 目录价：￥4449 |
| 货号：29665-5 mg | 规格：5 mg | 目录价：￥1072 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cenerimod
产品描述:
An S1P1 modulator (EC50 = 1 nM in a [35S]GTPɣS binding assay); selective for S1P1 over S1P2, -3, -4, and -5 (EC50s = >10,000, 228, 2,137, and 36 nM, respectively); decreases TGF-β-induced increases in collagen levels in primary mouse skin fibroblasts at 5 µM; inhibits CD4+ T cell, CD8+ T cell, and CD11b+ cell infiltration, reduces IL1b, Il6, and Il13 expression, as well as decreases fibrosis in the skin of a mouse model of sclerodermatous chronic graft versus host disease induced by allogenic bone marrow transplant at 10 mg/kg per day; reduces paralysis and spinal cord demyelination in a mouse model of EAE at 6 mg/kg per day for 32 days
保存温度:
-20
运输温度:
-20
预期分子量:
453.53086
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1262414-04-9
分子式:
C25H31N3O5
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