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折扣/货期| 货号：24159-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：24159-10 mg | 规格：10 mg | 目录价：￥2050 |
| 货号：24159-25 mg | 规格：25 mg | 目录价：￥4502 |
| 货号：24159-5 mg | 规格：5 mg | 目录价：￥1380 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ceralifimod
别名:
ONO-4641
产品描述:
An agonist of S1P1 and S1P5 receptors (Kis = 0.626 and 0.574 nM, respectively); selective for S1P1 and S1P5 over S1P2-4 (Kis = >5,450, >5,630, and 28.8 nM, respectively); induces calcium influx in CHO-K1 cells overexpressing S1P1 (EC50 = 1 nM) and cAMP accumulation in CHO-K1 cells overexpressing S1P1 or S1P5 (EC50s = 0.027 and 0.33 nM, respectively); reduces paw edema in a rat model of CIA at 0.03 and 0.1 mg/kg; delays disease onset and inhibits lymphocyte infiltration of the spinal cord in a rat model of EAE; prevents disease relapse in a non-obese diabetic mouse model of relapsing-remitting EAE
保存温度:
-20
运输温度:
-20
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
891859-12-4
分子式:
C27H33NO4
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