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折扣/货期| 货号：19374-1 mg | 规格：1 mg | 目录价：￥429 |
| 货号：19374-10 mg | 规格：10 mg | 目录价：￥1889 |
| 货号：19374-25 mg | 规格：25 mg | 目录价：￥3631 |
| 货号：19374-5 mg | 规格：5 mg | 目录价：￥1260 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ceritinib
别名:
LDK 378
产品描述:
An ALK inhibitor (IC50 = 0.2 nM); selective for ALK over IGF-1R, InsR, STK22D, and FLT3 (IC50s = 8, 7, 23, and 60 nM, respectively) as well as a panel of 25 additional kinases (IC50s = >0.26 μM for all); inhibits the proliferation of Ba/F3 cells expressing the fusion protein NPM-ALK or ELM4-ALK (IC50s = 0.02 and 0.021 μM, respectively), as well as several crizotinib-resistant NPM-ALK and ELM4-ALK mutants; reduces tumor growth in an H2228 NSCLC rat xenograft model at 10 mg/kg per day and induces tumor regression at 25 mg/kg per day; induces tumor regression in a Karpas299 lymphoma rat xenograft model at 25 and 50 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
558.1
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1032900-25-6
分子式:
C28H36ClN5O3S
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