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折扣/货期| 货号：AG-CR1-0071-M001 | 规格：1 mg | 目录价：￥360 |
| 货号：AG-CR1-0071-M005 | 规格：5 mg | 目录价：￥720 |
| 货号：AG-CR1-0071-M025 | 规格：25 mg | 目录价：￥2160 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Chelerythrine chloride
别名:
NSC 36405; 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
产品描述:
Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase [1, 5]. Antiplatelet, anti-inflammatory, antibacterial and antitumor compound [1, 2, 9, 12, 15]. Apoptosis inducer in cancer cells in vitro and in vivo [3, 9]. Activates MAPK and JUNK signaling pathways [4, 8]. Affects translocation of PKC from cytosol to plasma membrane [6]. Neurite outgrowth stimulator [7]. Inhibits binding of BclXL to Bak (IC50 = 1.5 µM) or Bad proteins and stimulates apoptosis in several cancer cell lines [10, 13]. Blocks human P2X7 receptor [11]. Induces cell cycle arrest in G1 phase [14]. Specific cyclooxygenase-2 inhibitor [15].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
383.8
产品形式:
solid
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
3895-92-9
分子式:
C21H18ClNO4
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