| 货号:21184-1 mg | 规格:1 mg | 目录价:¥5708 |
| 货号:21184-500 µg | 规格:500 µg | 目录价:¥3578 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Chk2 Inhibitor
别名:
SC-203885
产品描述:
A Chk2 inhibitor (IC50 = 13.5 nM); selective for Chk2 over Chk1 (IC50 = 220.4 nM); inhibits Chk2 autophosphorylation at Ser516 in non-cancerous 184B5 cells that contain wild-type p53 and in MDA-MB-231 cells that contain mutated p53 at 0.1-30 µM; enhances survival of 184B5, but not MDA-MB-231, cells following ionizing radiation; inhibits PMA-induced production of IL-2 in Jurkat cells and LPS-induced TNF-α production in THP-1 cells (IC50s = 3.5 and 8.2 µM, respectively); inhibits the growth of CEM leukemia T cells (GI50 = 1.73 µM)
保存温度:
-20
运输温度:
-20
预期分子量:
295.3
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
724708-21-8
分子式:
C15H13N5O2
促销活动
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