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折扣/货期| 货号：60-861 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CHM Antibody
别名:
Rab proteins geranylgeranyltransferase component A 1, Choroideremia protein, Rab escort protein 1, REP-1, TCD protein, CHM, REP1, TCD
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes component A of the RAB geranylgeranyl
transferase holoenzyme. In the dimeric holoenzyme, this subunit
binds unprenylated Rab GTPases and then presents them to the
catalytic Rab GGTase subunit for the geranylgeranyl transfer
reaction. Rab GTPases need to be geranylgeranyled on either one or
two cysteine residues in their C-terminus to localize to the
correct intracellular membrane. Mutations in this gene are a cause
of choroideremia; also known as tapetochoroidal dystrophy (TCD).
This X-linked disease is characterized by progressive dystrophy of
the choroid, retinal pigment epithelium and retina. Alternative
splicing results in multiple transcript variants encoding different
isoforms.
Accession #:
P24386
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