深圳欣博盛生物科技有限公司 a1

CHMFL-BMX-078
货号:36828-10 mg 规格:10 mg 目录价:¥1983
货号:36828-25 mg 规格:25 mg 目录价:¥3605
货号:36828-5 mg 规格:5 mg 目录价:¥1313
货号:36828-50 mg 规格:50 mg 目录价:¥6553
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CHMFL-BMX-078
产品描述:
An irreversible BMX inhibitor (IC50 = 11 nM); selectively inhibits the growth of Ba/F3 cells expressing BMX over Ba/F3 cells expressing Abl, c-Kit, PDGFRα, or PDGFRβ (GI50s = 0.016, 2.56, 2.01, 0.67, and 0.91 µM, respectively), as well as Ba/F3 cells expressing FLT3, EGFR, JAK3, or Blk (GI50s = >10 µM for all); inhibits the growth of 22Rv1, DU145, PC3, Hb-c, J82, T24, and ACHN cancer cells (GI50s = 3.45-8.98 µM); restores vemurafenib-induced cytotoxicity in vemurafenib-resistant A375 cells; reduces tumor weight and enhances vemurafenib-induced reduction of tumor weight in a vemurafenib-resistant A375 mouse xenograft model at 15 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
625.67458
产品形式:
A solid
纯度:
≥90%
CAS号:
1808288-51-8
分子式:
C33H35N7O6
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询