| 货号:12084-10 mg | 规格:10 mg | 目录价:¥643.2 |
| 货号:12084-5 mg | 规格:5 mg | 目录价:¥348.4 |
| 货号:12084-50 mg | 规格:50 mg | 目录价:¥2613 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CI-994
别名:
Goe 5549|N-Acetyldinaline|PD 123654|Tacedinaline
产品描述:
An inhibitor of HDAC1, -2, and -3 (IC50s = 0.9, 0.9, and 1.2 µM, respectively); selective for these HDACs over HDAC8 (IC50 = >20 µM); inhibits the growth of HCT116 colon cancer cells but not HMECs (IC50s = 4 and >50 µM, respectively); increases survival time in a rat model of 9,10-dimethyl-1,2-benzathracene-induced leukemia at 11.85 mg/kg twice per day; reduces tumor growth in an LNCaP mouse xenograft model, as well as in a Panc02 murine pancreatic cancer model; reduces neutrophil accumulation, inflammatory cytokine expression, and neuronal loss in a mouse model of spinal cord injury at 1, 10, and 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
269.3
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
112522-64-2
分子式:
C15H15N3O2
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