深圳欣博盛生物科技有限公司 a1

Ciclopirox
货号:16021-1 g 规格:1 g 目录价:¥8522.4
货号:16021-100 mg 规格:100 mg 目录价:¥1206
货号:16021-250 mg 规格:250 mg 目录价:¥2626.4
货号:16021-500 mg 规格:500 mg 目录价:¥4676.6
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ciclopirox
别名:
HOE 296b
产品描述:
An iron chelator, antifungal, and anticancer agent; inhibits HIF-PH2 (IC50 = 1.58 μM), an effect that is reduced in the presence of iron; stabilizes HIF-1α under normoxic conditions in rat glomus cells at 5 μM; active against clinical isolates of T. rubrum, T. mentagrophytes, and C. albicans (MICs = 0.03-0.5, 0.03-0.5, and 0.06-0.5 μg/ml, respectively) and inhibits growth of T. mentagrophytes on porcine skin ex vivo when applied topically; inhibits proliferation of Rh30, HT-29, and MDA-MB-231 cells in a concentration-dependent manner; halts the cell cycle at the G1/G0 phase and induces apoptosis in Rh30 cells; reduces tumor growth in an MDA-MB-231 mouse xenograft model at 25 mg/kg
保存温度:
22
运输温度:
22
预期分子量:
207.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
29342-05-0
分子式:
C12H17NO2
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