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折扣/货期| 货号：42394-1 mg | 规格：1 mg | 目录价：￥415 |
| 货号：42394-10 mg | 规格：10 mg | 目录价：￥3725 |
| 货号：42394-25 mg | 规格：25 mg | 目录价：￥8777 |
| 货号：42394-5 mg | 规格：5 mg | 目录价：￥1970 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CJ-033466
产品描述:
A 5-HT4 receptor partial agonist; induces cAMP accumulation in HEK293 cells expressing human 5-HT4D receptors and relaxation of rat tunica muscularis mucosae strips (EC50s = 0.927 and 1.3 nM, respectively); selectively binds to 5-HT4D over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, and 5-HT2B receptors (Kis = 1.26, >4,820, >5,070, 2,150, 1,400, and 2,900 nM, respectively) and 5-HT3, 5-HT7, and dopamine D2 receptors (Kis = 4,590, >3,890, and 2,150 nM, respectively), as well as a panel of >50 additional receptors at 1,000 nM; increases gastric antral motility in conscious dogs in the fasted or postprandial states at 0.3 mg/kg; reverses clonidine-induced decreases in gastric emptying in a dog model of gastroparesis; induces superoxide production in a light-dependent manner and is phototoxic to NIH3T3 fibroblasts (IC50s = 11.4 and 203.3 µg/ml in the presence and absence of light, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
377.91142
产品形式:
A solid
纯度:
≥98%
CAS号:
519148-48-2
分子式:
C19H28ClN5O
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