深圳欣博盛生物科技有限公司 a1

Claudin 3 Antibody / CLDN3
货号:RQ5714 规格:100 ug 目录价:¥6488.05
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Claudin 3 Antibody / CLDN3
产品描述:
Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens, and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane. This protein is highly overexpressed in uterine carcinosarcoma. This protein is also predominantly present in brain endothelial cells, where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology.
反应种属:
Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IF
同种型:
Rabbit IgG
免疫原:
Amino acids RDKYAPTKILYSAPRST from the mouse protein were used as the immunogen for the Claudin 3 antibody.
克隆性:
Polyclonal
纯化方式:
Affinity purified
保存温度:
After reconstitution, the Claudin 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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