| 货号:AG-40A-0057-C050 | 规格:50 ug | 目录价:¥3780 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Clusterin (nuclear form) (mouse) (rec.) (His)
别名:
TRPM-2; Apolipoprotein J; APO-J; CLI; CLU; SGP-2
产品描述:
Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
宿主来源:
E. coli
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
预期分子量:
~45kDa (SDS-PAGE)
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
内毒素水平:
<1EU/µg purified protein (LAL test; Lonza).
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