官网链接
折扣/货期| 货号：AG-CR1-3567-M001 | 规格：1 mg | 目录价：￥360 |
| 货号：AG-CR1-3567-M005 | 规格：5 mg | 目录价：￥900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Colcemid
别名:
Demecolcine; BRN 2822892
产品描述:
Anti-cancer compound [2, 6, 7, 10, 11, 14]. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle [11, 12, 14]. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation) [1, 4, 5, 14]. Inhibits mitosis during cell division at metaphase by inhibiting spindle formation [2, 5, 7, 8, 14]. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center [14]. Apoptosis inducer [9, 13]. Thrombopoietic agent [3].
宿主来源:
Semisynthetic from colchicine (Prod. No. AG-CN2-0048).
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
371.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
477-30-5
分子式:
C21H25NO5
溶解度:
Soluble in ethanol, DMSO or chloroform.
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