官网链接
折扣/货期| 货号：42738-1 mg | 规格：1 mg | 目录价：￥1461 |
| 货号：42738-10 mg | 规格：10 mg | 目录价：￥7303 |
| 货号：42738-5 mg | 规格：5 mg | 目录价：￥5119 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Corosolic Acid β
别名:
CAβ
产品描述:
A synthetic pentacyclic triterpenoid; has been used in the generation of LNPs for the delivery of mRNA and siRNA in vitro and in vivo; inhibits glycogen phosphorylase (IC50 = 82.5 µM for the rabbit muscle enzyme); LNPs containing corosolic acid β and encapsulating an mRNA reporter show greater transfection efficiency than those containing cholesterol in 4T1, B16/F10, and HeLa cells; corosolic acid β-containing LNPs selectively accumulate in tumors and do not accumulate in the liver compared with cholesterol-containing LNPs, which accumulate in both, following intratumoral injection; LNPs containing corosolic acid β and encapsulating siRNA targeting mRNA encoding Bcl-2 decrease tumor volume and lung metastasis and increase survival in a 4T1 murine mammary carcinoma model
保存温度:
-20
运输温度:
-20
预期分子量:
514.791
产品形式:
A 10 mg/ml solution in methyl acetate
纯度:
≥98%
CAS号:
958237-73-5
分子式:
C33H54O4
促销活动
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