Corynoline-抑制剂-深圳欣博盛生物科技有限公司

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Corynoline

品牌：Cayman

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说明书

折扣/货期

货号：30712-1 mg	规格：1 mg	目录价：￥724
货号：30712-10 mg	规格：10 mg	目录价：￥3886
货号：30712-5 mg	规格：5 mg	目录价：￥2801

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Corynoline

别名:

(+)-Corynoline|(d)-Corynoline|13-methyl-Chelidonine|CRL

产品描述:

An isoquinoline alkaloid with diverse biological activities; an inhibitor of acetylcholinesterase (IC50 = 30.6 µM); an inhibitor of BACE1 (IC50s = 33.59 and 89.07 µM for FRET and immobilized enzyme reactive assays, respectively); decreases LPS-induced NF-κB activation and reverses LPS-induced decreases in Nrf2 and HO-1 protein levels in HUVECs; increases the survival rate in a mouse model of LPS- and heat-killed E. coli-induced sepsis at 10, 20, and 40 mg/kg; selectively inhibits proliferation of B16/F10 mouse and A375 human melanoma cells (IC50s = 12.87 and 10.47 µM, respectively) over non-cancerous melanocytes (IC50 = 126.61 µM); reduces tumor growth in a B16/F10 mouse melanoma model at 20 mg/kg

保存温度:

-20

运输温度:

-20

预期分子量:

367.39518

产品形式:

A crystalline solid

纯度:

≥95%

来源:

Plant/Corydalis bungeana Turcz.