深圳欣博盛生物科技有限公司 a1

Cotadutide (acetate)
货号:40714-1 mg 规格:1 mg 目录价:¥1460.6
货号:40714-10 mg 规格:10 mg 目录价:¥11684.8
货号:40714-25 mg 规格:25 mg 目录价:¥23718
货号:40714-5 mg 规格:5 mg 目录价:¥6579.4
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cotadutide (acetate)
别名:
MEDI0382
产品描述:
A synthetic peptide and peptide dual agonist of GLP-1R and GCGR; increases cAMP accumulation in CHO cells overexpressing recombinant human GLP-1R or GCGR (EC50s = 6.9 and 10.2 pM, respectively); reduces food intake and fat mass, as well as improves glucose tolerance in DIO mice at 10 nmol/kg; reduces food intake and body weight in wild-type, but not Glp1r knockout mice; reduces the hepatic lipid percentage in both wild-type and Glp1r knockout mice; reduces total hepatic triglycerides, diglycerides, cholesterol, and free fatty acids, as well as reduces hepatic inflammation and fibrosis, in an ob/ob mouse model of NASH induced by a high-trans fat, high-fructose, and high-cholesterol diet at 10 nmol/kg
保存温度:
-20
运输温度:
-20
预期分子量:
3788.1
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C167H252N42O55 • C2H4O2
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