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折扣/货期| 货号：45039-1 mg | 规格：1 mg | 目录价：￥911 |
| 货号：45039-10 mg | 规格：10 mg | 目录价：￥8201 |
| 货号：45039-5 mg | 规格：5 mg | 目录价：￥4328 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Crinecerfont
别名:
NBI 74788|SSR 125543
产品描述:
A CRF1 antagonist (Ki = 1.9 nM); selective for CRF1 over CRF2α and a panel of 125 receptors, transporters, ion channels, and enzymes at 10 µM; inhibits CRF-induced cAMP production in Y79 cells (IC50 = 3 nM) and CRF-induced ACTH secretion in AtT-20 cells at 3, 30, and 100 nM; prevents restraint stress-induced increases in plasma ACTH levels in rats at 10 mg/kg, p.o.; increases punished responding in the Vogel punished drinking task, indicating anxiolytic-like activity, in mice and decreases immobility time in the forced swim test in rats; decreases cumulative weight gain and increases protein gain in fa/fa obese but not lean rats at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
483.042403
产品形式:
A solid
纯度:
≥98%
CAS号:
752253-39-7
分子式:
C27H28ClFN2OS
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