CRYAB Antibody / Alpha B Crystallin-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

CRYAB Antibody / Alpha B Crystallin

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ5808

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CRYAB Antibody / Alpha B Crystallin

产品描述:

Alpha-crystallin B chain is a protein that in humans is encoded by the CRYAB gene. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IF, FACS, IHC-P, Direct ELISA

同种型:

Rabbit IgG

免疫原:

Recombinant human protein (amino acids E30-Q151) was used as the immunogen for the CRYAB antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Affinity purified

保存温度:

After reconstitution, the CRYAB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

您可能感兴趣的产品

Lyve-1 (human) antibody

货号：RLT-102-PABI50

Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep

货号：NB-58050-01

Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep