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折扣/货期| 货号：38766-10 mg | 规格：10 mg | 目录价：￥5012 |
| 货号：38766-25 mg | 规格：25 mg | 目录价：￥11846 |
| 货号：38766-5 mg | 规格：5 mg | 目录价：￥2787 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CS 2164
别名:
Chiauranib|Ibcasertib
产品描述:
A multi-kinase inhibitor; inhibits VEGFR1, -2, and -3 (IC50s = 8, 7, and 9 nM, respectively), PDGFRα and PDGFRβ (IC50s = 1 and 93 nM), c-Kit (IC50 = 4 nM), Aurora B kinase (IC50 = 9 nM), and FMS (IC50 = 7 nM); selective for these kinases over a panel of 72 additional kinases, 76 GPCRs, two phosphatases, and nine ion channels (IC50s = >100 nM for all); inhibits VEGF-induced proliferation of HUVECs (GI50 = 20.7 nM) and PDGF-induced proliferation of NIH3T3 cells (GI50 = 44.16 nM); reduces tumor vascularization and tumor growth in a COLO 320 mouse xenograft model at 20 mg/kg; reduces tumor volume in A549, HCT-8, SMMC-7721, and MGC803 mouse xenograft models from 2.5-40 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
435.47406
产品形式:
A solid
纯度:
≥98%
CAS号:
1256349-48-0
分子式:
C27H21N3O3
促销活动
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