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折扣/货期| 货号：10007923-10 mg | 规格：10 mg | 目录价：￥1286.4 |
| 货号：10007923-25 mg | 规格：25 mg | 目录价：￥3041.8 |
| 货号：10007923-5 mg | 规格：5 mg | 目录价：￥696.8 |
| 货号：10007923-50 mg | 规格：50 mg | 目录价：￥5306.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CUDA
产品描述:
Epoxyeicosatrienoic acid (EpETrE; EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity.{12391} Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs; DHETs) thereby diminishing their activity. CUDA is an inhibitor of sEH exhibiting IC50 values of 11.1 nM and 112 nM for the mouse and human enzymes, respectively.{14064} In COS-7 cells, 10 µM CUDA blocks conversion of 1 µM 14,15-EET to 14,15-DHET by 94%. CUDA activates peroxisome proliferator-activated receptor α (PPARα) 8-fold at a concentration of 10 µM but exhibits no affect on PPAR.delta. or PPARγ.{13447}
保存温度:
-20
运输温度:
-20
预期分子量:
340.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
479413-68-8
分子式:
C19H36N2O3
促销活动
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