官网链接
折扣/货期| 货号：20943-1 mg | 规格：1 mg | 目录价：￥12810 |
| 货号：20943-500 µg | 规格：500 µg | 目录价：￥7075 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cyclopamine-KAAD
产品描述:
A potent inhibitor of hedgehog signaling (IC50 = 20 nM in a Shh-LIGHT2 assay); blocks binding of BODIPY-cyclopamine to cells expressing Smo in a dose-dependent manner; cell-permeable and binds to SmoA1 to promote its exit from the endoplasmic reticulum; inhibits the invasion and migration (45.9 and 43.3% inhibition, respectively) of Bel-7402 hepatocarcinoma cells; decreases the expression of nuclear Gli1 and cytosoloic MMP-9, pERK1, and pERK2 proteins in a dose-dependent manner; increases TRAIL-mediated cell death in NCH82 and NCH89 human glioblastoma cultures; upregulates expression of DR4 and DR5 in LN229 and U251 glioma cells
保存温度:
-20
运输温度:
-20
预期分子量:
698
产品形式:
A solid
纯度:
≥95%
CAS号:
306387-90-6
分子式:
C44H63N3O4
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