深圳欣博盛生物科技有限公司 a1

Cyclovirobuxine D
货号:22260-10 mg 规格:10 mg 目录价:¥1072
货号:22260-25 mg 规格:25 mg 目录价:¥2318
货号:22260-5 mg 规格:5 mg 目录价:¥590
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cyclovirobuxine D
别名:
CVB-D|NSC 91722
产品描述:
An alkaloid with diverse biological activities; ERG channel blocker (IC50 = 19.7 μM using whole-cell patch-clamp electrophysiology in HEK293 cells expressing the human receptor); increases the amount and rate of calcium release from intracellular stores in healthy neonatal rat cardiac myocytes and those isolated from adult rats with heart failure in a concentration-dependent manner; increases expression of Ryr2 and Serca2a and decreases expression of Ncx; reduces mortality and improves cardiac function in a rat model of congestive heart failure; inhibits doxorubicin-induced myocardial apoptosis and mitochondrial cytochrome C release in mice when preadministered at a dose of 1mg/kg per day for four days; induces cellular autophagy and inhibits growth of MCF-7 breast cancer cells and induces mitochondrial apoptosis in MGC803 and MKN26 gastric cancer cells
保存温度:
-20
运输温度:
-20
预期分子量:
402.7
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
860-79-7
分子式:
C26H46N2O
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