深圳欣博盛生物科技有限公司 a1

CYP7A1 Antibody
货号:RQ5717 规格:100 ug 目录价:¥6488.05
产品详情
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产品名称:
CYP7A1 Antibody
产品描述:
CYP7A1 (Cytochrome P450 Subfamily VIIA Polypeptide 1), also called CYP7 or CHOLESTEROL 7-ALPHA-HYDROXYLASE, is an enzyme that in humans is encoded by the CYP7A1 gene. Using both mouse-human somatic cell hybrids and in situ chromosomal hybridization, Cohen et al.(1992) mapped the CYP7 gene to 8q11-q12. By transfection of reporter constructs, mutation analysis, and DNase footprinting, Molowa et al.(1992) identified areas of the CYP7A1 promoter region that showed hepatocyte-specific activation. They found HNF3 to be an activator of CYP7A1 activity. Agellon et al.(2002) found that wildtype mice and mice transgenic for human CYP7A1 respond differently to cholesterol feeding. Cholesterol feeding stimulated Cyp7a1 mRNA abundance and enzymatic activity in wildtype mice, but repressed human CYP7A1 mRNA and activity in transgenic mice.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, FACS, IF, IHC-P, Direct ELISA
同种型:
Rabbit IgG
免疫原:
Recombinant human protein (amino acids I10-L504) was used as the immunogen for the CYP7A1 antibody.
克隆性:
Polyclonal
纯化方式:
Affinity purified
保存温度:
After reconstitution, the CYP7A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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