深圳欣博盛生物科技有限公司 a1

CYY292
货号:39831-1 mg 规格:1 mg 目录价:¥683
货号:39831-10 mg 规格:10 mg 目录价:¥5092
货号:39831-5 mg 规格:5 mg 目录价:¥2720
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CYY292
产品描述:
A PDGFR and FGFR inhibitor (IC50s = 5.35, 4.6, 28, 28, and 78 nM for PDGFRα, PDGFRβ, FGFR1, -2, and -3, respectively); selective for these kinases over FGFR4 (IC50 = >1,000 nM) but also inhibits c-Kit, VEGFR2, VEGFR1, and IGF-1R (IC50s = 67, 33, 36, and 75 nM, respectively), as well as EGFR, BTK, Cdk4/cyclin D3, and MET (IC50s = 128, 198, 214, and 396 nM, respectively); inhibits the proliferation of MG-63, U2OS, MNNG/HOS, and Saos-2 cells (IC50s = 0.84, 0.76, 1.36, and 0.72 µM, respectively); inhibits the migration and invasion of U87MG and LN-229 cells at 0.3 and 0.5 µM; decreases tumor volume and increases survival in a U87MG orthotopic mouse xenograft model 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
444.53244
产品形式:
A solid
纯度:
≥98%
CAS号:
2644673-04-9
分子式:
C24H28N8O
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询