| 货号:27668-1 mg | 规格:1 mg | 目录价:¥657 |
| 货号:27668-10 mg | 规格:10 mg | 目录价:¥4744 |
| 货号:27668-25 mg | 规格:25 mg | 目录价:¥8643 |
| 货号:27668-5 mg | 规格:5 mg | 目录价:¥2546 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CZ415
产品描述:
An mTOR inhibitor (Kd = 6.3 nM); 1,000-fold selective for mTOR over a panel of 285 kinases; inhibits phosphorylation of S6RP and Akt in HEK293T cells (IC50s = 14.5 and 14.8 nM, respectively); inhibits IFN-γ secretion in IL-2, anti-CD3, and anti-CD28 antibody-stimulated human whole blood (IC50 = 226 nM); reduces fore paw joint erythema and swelling in a mouse model of collagen-induced arthritis at 10 mg/kg; inhibits intratumor mTOR activity and reduces tumor growth in an OCC-1 oral cavity carcinoma mouse xenograft model at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
459.56296
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1429639-50-8
分子式:
C22H29N5O4S
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