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折扣/货期| 货号：21877-1 g | 规格：1 g | 目录价：￥1394 |
| 货号：21877-5 g | 规格：5 g | 目录价：￥4918 |
| 货号：21877-500 mg | 规格：500 mg | 目录价：￥804 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dacarbazine
别名:
NCI C04717|NSC 45388
产品描述:
A DNA alkylating prodrug; converted into a methyldiazonium cation that alkylates DNA at all phases of the cell cycle and induces apoptosis; inhibits the growth of B16/F1, A-875, and SK-MEL-5 melanoma and non-cancerous WI-38 lung fibroblast and L-02 hepatocyte cell lines (IC50s = 260, 287, 380, 526, and 367 μM, respectively); toxicity to 518A2 and SK-MEL-28 melanoma cell lines increases in a time-dependent manner (IC50s = 121 and >400, respectively, at 1 hour and 2.5 and 50 μM, respectively, at 96 hours); decreases tumor volume by 59.1% in a B16/F1 murine melanoma model in mice (70 mg/kg, once every 2 days)
保存温度:
-20
运输温度:
-20
预期分子量:
182.2
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
4342-03-4
分子式:
C6H10N6O
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