官网链接
折扣/货期| 货号：24671-10 mg | 规格：10 mg | 目录价：￥549.4 |
| 货号：24671-100 mg | 规格：100 mg | 目录价：￥3926.2 |
| 货号：24671-250 mg | 规格：250 mg | 目录价：￥9112 |
| 货号：24671-50 mg | 规格：50 mg | 目录价：￥2103.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dapansutrile
别名:
3-methanesulfonyl Propanenitrile
产品描述:
An NLRP3 inflammasome inhibitor; inhibits the release of IL-1β and decreases caspase-1 levels in LPS-stimulated J774A.1 murine macrophages, HMDMs, and primary human blood neutrophils; selective for NLRP3 over NLRP4 and AIM2 inflammasomes at concentrations up to 100 μM; inhibits ASC oligomerization and NLRP3 association with caspase-1 and ASC in LPS- and nigericin-stimulated J774A.1 cells; reduces MPO, CXCL1, and IL-6 levels in peritoneal fluid as well as IL-1β levels in liver, lung, spleen, and skeletal muscle in a mouse model of LPS-induced systemic inflammation; increases markers of oxidative metabolism in muscle in mouse model of LPS-induced systemic inflammation; reduces IL-1β release in blood monocytes isolated from patients with CAPS
保存温度:
-20
运输温度:
-20
预期分子量:
133.2
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
54863-37-5
分子式:
C4H7NO2S
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询