深圳欣博盛生物科技有限公司 a1

DBH Antibody / Dopamine beta Hydroxylase
货号:RQ5573 规格:100 ug 目录价:¥6488
产品详情
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产品名称:
DBH Antibody / Dopamine beta Hydroxylase
产品描述:
Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC1.14.17.1) that in humans is encoded by the DBH gene. Dopamine beta-hydroxylase catalyzes the chemical reaction. It is mapped to 9q34.2. The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, Direct ELISA
同种型:
Rabbit IgG
免疫原:
A human recombinant protein (amino acids S40-N545) was used as the immunogen for the DBH antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Affinity purified
保存温度:
After reconstitution, the DBH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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