DDR1 Antibody-多抗-深圳欣博盛生物科技有限公司

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DDR1 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R30978

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DDR1 Antibody

产品描述:

Discoidin domain receptor family, member 1, also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a DDR that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment. Bhatt et al.(2000) showed that the protein was highly expressed in the cerebellum of developing and adult mouse brain, and that both DDR1 and Collagen IV were highly expressed in the pial layer of the cerebellar cortex. Cocultures of Collagen I- and IV-expressing mouse pial cells with DDR1-expressing granule cells resulted in granule cell neurite extension. Inhibition of collagen-DDR1 signaling reduced granule cell neurite elongation.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

Rabbit IgG

免疫原:

An amino acid sequence from the C-terminus of human DDR1/RKT6 (FSQLHRFLAEDALNTV) was used as the immunogen for this DDR1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the DDR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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