深圳欣博盛生物科技有限公司 a1

Dehydrolithocholic Acid
货号:29544-10 mg 规格:10 mg 目录价:¥482
货号:29544-100 mg 规格:100 mg 目录价:¥2265
货号:29544-250 mg 规格:250 mg 目录价:¥3940
货号:29544-50 mg 规格:50 mg 目录价:¥1380
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Dehydrolithocholic Acid
别名:
3-keto LCA|3-keto Lithocholate|3-keto Lithocholic Acid|3-KLCA|3-oxo LCA|3-oxo Lithocholate|3-oxo Lithocholic Acid
产品描述:
A major metabolite of lithocholic acid; formed from LCA by CYP3A4; an agonist of TGR5 (EC50 = 0.27 μM), VDR (EC50 = 3 μM), and FXR in cell-based reporter assays; binds to human PXR (IC50 = 15 μM) and activates mouse and human PXRs in cell-based reporter assays at 100 μM; binds to RORγt (Kd = 1.13 μM for the recombinant human ligand-binding domain) and decreases its activity in a cell-based reporter assay at 10 μM; inhibits the differentiation of TH17 cells at 20 μM
保存温度:
-20
运输温度:
-20
预期分子量:
374.55672
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1553-56-6
分子式:
C24H38O3
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