| 货号:22433-10 mg | 规格:10 mg | 目录价:¥2720 |
| 货号:22433-25 mg | 规格:25 mg | 目录价:¥5682 |
| 货号:22433-5 mg | 规格:5 mg | 目录价:¥1434 |
| 货号:22433-50 mg | 规格:50 mg | 目录价:¥10640 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DEL-22379
产品描述:
An inhibitor of ERK dimerization (IC50 = ~0.5 μM for disruption of EGF-induced co-immunoprecipitation of ERK); has no effect on ERK phosphorylation or kinase activity (IC50s = >10 μM); inhibits cell growth in a panel of melanoma and colorectal cancer cell lines (IC50s = 150-400 nM); inhibits ERK dimerization in liver extract and tumor tissue and inhibits tumor progression in an A375 mouse xenograft model at 15 mg/kg; reduces tumor growth in a BRAF mutant colorectal cancer PDX mouse model
保存温度:
-20
运输温度:
-20
预期分子量:
444.5
产品形式:
A crystalline solid
纯度:
≥98% (mixture of rotamers)
CAS号:
181223-80-3
分子式:
C26H28N4O3
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