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折扣/货期| 货号：37975-1 mg | 规格：1 mg | 目录价：￥469 |
| 货号：37975-10 mg | 规格：10 mg | 目录价：￥2720 |
| 货号：37975-5 mg | 规格：5 mg | 目录价：￥1474 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dendrogenin A
别名:
DDA
产品描述:
A selective LXR modulator and ChEH inhibitor (Ki = 120 nM); inhibits 22(R)-hydroxy cholesterol-induced LXRβ and LXRα activation in a reporter assay (IC50s = 76 and 362 nM, respectively) but is also a partial agonist of LXRs, increasing protein levels of Nur77, NOR-1, LC3-I, and LC3-II in B16/F10 murine melanoma cells; selective for modulation of LXRα and LXRβ over PXR, AhR, VDR, RXRγ, RARα, PPARα, PPARγ, GR, AR, ERα, and ERβ at 2.5 µM; increases protein levels of LC3-II in B16/F10 and SK-MEL-28 cancer cells at 2.5 and 5 µM and induces autophagic cell death in the same cell types at 2.5 µM; reduces tumor growth in a B16/F10 murine model of melanoma and a TS/A murine mammary cancer model and induces cancer cell differentiation in vitro and in vivo
保存温度:
-20
运输温度:
-20
预期分子量:
513.79812
产品形式:
A solid
纯度:
≥95%
CAS号:
1191043-85-2
分子式:
C32H55N3O2
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