官网链接
折扣/货期| 货号：39664-1 mg | 规格：1 mg | 目录价：￥1112 |
| 货号：39664-10 mg | 规格：10 mg | 目录价：￥8308 |
| 货号：39664-25 mg | 规格：25 mg | 目录价：￥13829 |
| 货号：39664-5 mg | 规格：5 mg | 目录价：￥4985 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Difamilast
别名:
OPA 15406
产品描述:
A PDE4 inhibitor; selective for the PDE4 isoforms PDE4A, PDE4B, PDE4C, and PDE4D (IC50s = 0.0832, 0.0112, 0.2493 and 0.0738 µM, respectively) over PDE5A and PDE10A (IC50s = 4.793 and 1.4346 µM, respectively) and eight other PDEs (IC50s = >10 µM for all); increases intracellular cAMP levels in U937 cells at 0.01-10 µM; inhibits LPS-induced increases in TNF-α secretion from isolated human and mouse PBMCs (IC50s = 19 and 3.5 nM, respectively); decreases ear thickness and CD3+ T cell, eosinophil, and neutrophil lesion infiltrates in a mouse model of 2,4,6-trinitrochlorobenzene-induced chronic allergic contact dermatitis when applied topically at 3% w/v
保存温度:
-20
运输温度:
-20
预期分子量:
446.443946
产品形式:
A solid
纯度:
≥98%
CAS号:
937782-05-3
分子式:
C23H24F2N2O5
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询