| 货号:42535-1 mg | 规格:1 mg | 目录价:¥965 |
| 货号:42535-10 mg | 规格:10 mg | 目录价:¥6244 |
| 货号:42535-25 mg | 规格:25 mg | 目录价:¥10787 |
| 货号:42535-5 mg | 规格:5 mg | 目录价:¥4328 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Dipraglurant
别名:
ADX-48621
产品描述:
A negative allosteric modulator of mGluR5 (Ki = 21 nM); inhibits glutamate-induced calcium mobilization, IP1 accumulation, and ERK1/2 phosphorylation in HEK293A cells expressing rat mGluR5a (pKBs = 5.83, 6.5, and 6.67, respectively); increases drinking in the Vogel punished drinking task in rats, indicating anxiolytic-like activity, decreases marble burying in mice, and reduces immobility time in the forced swim test in mice (ED50s = 7.4, 43, and ~30 mg/kg, respectively); reduces chorea and dystonia scores in a macaque model of MPTP-induced PD-LID
保存温度:
-20
运输温度:
-20
预期分子量:
265.285103
产品形式:
A solid
纯度:
≥98%
CAS号:
872363-17-2
分子式:
C16H12FN3
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