DOG1 Antibody (TMEM16A)-多抗-深圳欣博盛生物科技有限公司

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DOG1 Antibody (TMEM16A)

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31414

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DOG1 Antibody (TMEM16A)

产品描述:

Anoctamin-1 (ANO1), also known as oral cancer overexpressed 2 (ORAOV2), Tumor-amplified and overexpressed sequence 2 (TMEM16A), and Discovered on gastrointestinal stromal tumors protein 1 (DOG1) is a protein that in humans is encoded by the ANO1 gene. This gene belongs to a family of membrane proteins containing 8 transmembrane segments, and it is mapped to 11q13.3. ANO1 is a candidate calcium-activated chloride channel that mediates receptor-activated chloride currents in diverse physiologic processes, and it is though to be responsible for a voltage-sensitive calcium-activated chloride current. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression Crofelemer, an antidiarrhoeal, inhibits this channel. ANO1/DOG1 has eight transmembrane domains, its pore is large and non-selective, allowing other negatively charged species to permeate.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

同种型:

Rabbit IgG

免疫原:

An amino acid sequence from the C-terminus of human ANO1/TMEM16A/DOG1 (KVLMVELFMREEQDKQQ) was used as the immunogen for this DOG1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the DOG1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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