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折扣/货期| 货号：15888-1 g | 规格：1 g | 目录价：￥询价 |
| 货号：15888-5 g | 规格：5 g | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Doxepin (hydrochloride)
产品描述:
A tricyclic antidepressant; binds to SERT and NET (Kds = 68 and 29.5 nM, respectively); a histamine H1 receptor antagonist (Ki = 1.23 nM); selectively binds to SERT and NET over DAT (Kd = 12,100 nM) and inhibits histamine H1 over H2, H3, and H4 receptors (Kis = 170, 39,810, and 15,135 nM, respectively); binds to the 5-HT2 receptor, as well as to muscarinic acetylcholine and α1-ARs (Kds = 27, 23, and 23.5 nM, respectively); decreases allodynia and hyperalgesia in a mouse model of chronic constriction injury-induced neuropathic pain at 10 mg/kg, i.p.; increases the distance traveled in the center of the open field test and reduces immobility time in the forced swim test in a mouse model of depression induced by chronic stress at 15 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
279.34
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1229-29-4
分子式:
C19H21NO • HCl
促销活动
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