| 货号:36229-1 mg | 规格:1 mg | 目录价:¥911 |
| 货号:36229-10 mg | 规格:10 mg | 目录价:¥7571 |
| 货号:36229-25 mg | 规格:25 mg | 目录价:¥14432 |
| 货号:36229-5 mg | 规格:5 mg | 目录价:¥3149 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DUB-IN-2
别名:
Deubiquitinase Inhibitor 2|Deubiquitinase-IN-2|DUBs Inhibitor 2|DUBs-IN-2|HY-50737A
产品描述:
An inhibitor of USP8 (IC50 = 280 nM); selective for USP8 over USP7 (IC50 = >100 µM); increases the level of PD-L1 in H460 cells at 2 µM and PC-9 cells at 2 and 4 µM; decreases tumor weight, tumor size, and lung metastasis and increases CD8+ T cell numbers within the primary tumor in a 4T1 murine mammary carcinoma model at 1 mg/kg every other day, i.p., when combined with an anti-PD-L1 antibody and paclitaxel
保存温度:
-20
运输温度:
-20
预期分子量:
275.26506
产品形式:
A solid
纯度:
≥95% (mixture of cis/trans isomers)
CAS号:
924296-19-5
分子式:
C15H9N5O
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