官网链接
折扣/货期| 货号：41594-10 mg | 规格：10 mg | 目录价：￥7906 |
| 货号：41594-100 mg | 规格：100 mg | 目录价：￥27859 |
| 货号：41594-5 mg | 规格：5 mg | 目录价：￥4650 |
| 货号：41594-50 mg | 规格：50 mg | 目录价：￥18572 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DUB-IN-3
别名:
Deubiquitinase Inhibitor 3|Deubiquitinase-IN-3|DUBs Inhibitor 3|DUBs-IN-3|HBX 90397
产品描述:
An inhibitor of USB8 (IC50 = 0.56 µM); selective for USP8 over USP7 (IC50 = >100 µM); an inhibitor of SARS-CoV-2 PLpro when Z-LRGG-AMC is used as a substrate (IC50 = 12.5 µM) but not when Ub-AMC is used as a substrate (IC50 = >10 µM); reduces GSH levels and cystine uptake, as well as increases ferrous iron and ROS levels, in HCCLM3 cells at 0.2 or 0.5 µM; decreases viability of HCCLM3 cells when used with RSL3, an effect that can be blocked by ferrostatin-1; reduces the proliferation, migration, and oncosphere formation ability of HCCLM3 and Hep3B hepatocellular carcinoma cells at 0.1 and 0.2 µM; reduces tumor growth and metastasis in HCCLM3 and Hep3B mouse models of metastatic lung cancer at 5 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
287.27576
产品形式:
A solid
纯度:
≥98%
CAS号:
924296-17-3
分子式:
C16H9N5O
促销活动
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