深圳欣博盛生物科技有限公司 a1

DuP-697
货号:70645-10 mg 规格:10 mg 目录价:¥2586
货号:70645-25 mg 规格:25 mg 目录价:¥6003
货号:70645-5 mg 规格:5 mg 目录价:¥1621
货号:70645-50 mg 规格:50 mg 目录价:¥11162
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DuP-697
产品描述:
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.{4313} When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2 than COX-1.{7452} The IC50 values for human recombinant COX-2 are 80 and 40 nM at 5 and 10 minutes, respectively.{8512} The IC50 for the inhibition of human recombinant COX-1 after the same time intervals is 9 µM.{8512} DuP-697 also attenuates the COX-1 inhibitory activity of non-selective COX inhibitors such as indomethacin.{8048}
保存温度:
-20
运输温度:
-20
预期分子量:
411.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
88149-94-4
分子式:
C17H12BrFO2S2
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