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折扣/货期| 货号：RQ5389 | 规格：100 ul | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E-Cadherin Antibody / CDH1
产品描述:
The CDH1 gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. [RefSeq]
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
Rabbit IgG
免疫原:
A synthetic peptide specific to human E-Cadherin / CDH1 was used as the immunogen for the E-Cadherin antibody.
克隆性:
Rabbit Monoclonal
克隆号:
COH-3
纯化方式:
Affinity purified
保存温度:
Store the E-Cadherin antibody at -20oC.
产品形式:
Purified
存储溶液:
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
产地:
美国
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