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折扣/货期| 货号：21658-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：21658-10 mg | 规格：10 mg | 目录价：￥4060 |
| 货号：21658-25 mg | 规格：25 mg | 目录价：￥8429 |
| 货号：21658-5 mg | 规格：5 mg | 目录价：￥2144 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E7449
产品描述:
An inhibitor of PARP1, PARP2, and TNKS1/2 (IC50s = 1, 1.2, and 50-11 nM, respectively); selective for PARP1, PARP2, and TNKS1/2 over PARP3 and PARP6-15 (IC50s = >3 μM); inhibits growth of DT40 cells in a PARP-dependent manner (IC50s = 3.2 and >15 μM for wild-type and PARP-/- cells, respectively); decreases expression of Wnt/β-catenin signaling pathway proteins in SW480 cells; enhances antitumor activity of temozolomide and carboplatin in a B16/F10 isograft model and MX-1 mouse xenograft model, respectively; inhibits tumor growth in a BRCA1 mutant MDA-MB-436 breast cancer mouse xenograft model at 30 and 100 mg/kg per day; delays hair regrowth in mice following hair removal
保存温度:
-20
运输温度:
-20
预期分子量:
317.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1140964-99-3
分子式:
C18H15N5O
促销活动
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