| 货号:19719-1 mg | 规格:1 mg | 目录价:¥563 |
| 货号:19719-10 mg | 规格:10 mg | 目录价:¥4060 |
| 货号:19719-25 mg | 规格:25 mg | 目录价:¥8750 |
| 货号:19719-5 mg | 规格:5 mg | 目录价:¥2452 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
EAI045
产品描述:
A potent inhibitor of mutant EGFRs (IC50s = 0.076, 0.049, 0.002, and 1.6 μM for recombinant EGFRL858R, EGFRT790M, EGFRL858R/T790M, and wild-type EGFR, respectively); inhibits phosphorylation of EGFR in a concentration-dependent manner in H1975 cells; reduces proliferation of Ba/F3 cells expressing EGFRL858R/T790M and EGFRL858R/T790M/I941R from 0.01-10 μM; induces tumor regression and reduces EGFR signaling in mice bearing EGFRL858R/T790M, EGFRExon19del/T790M, and EGFRL858R/T790M/C797S tumors at 60 mg/kg/day with cetuximab
保存温度:
-20
运输温度:
-20
预期分子量:
383.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1942114-09-1
分子式:
C19H14FN3O3S
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