EED Antibody-多抗-深圳欣博盛生物科技有限公司

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EED Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F53203-0.08ML	规格：0.08 ml	目录价：￥2962
货号：F53203-0.4ML	规格：0.4 ml	目录价：￥6344

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

EED Antibody

产品描述:

Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark (By similarity). The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. Plays a role in X chromosome inactivation (XCI), in which one of the two X chromosomes in female mammals is transcriptionally silenced to equalize X-linked gene dosage with XY males. Required for stable maintenance of XCI in both embryonic and extraembryonic tissues. May prevent transcriptional activation of facultative heterochromatin during differentiation. Required for development of secondary trophoblast giant cells during placental development. May regulate hippocampal synaptic plasticity in the developing brain.

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

This EED antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 269-303 amino acids from the central region of mouse Eed.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

Aliquot the EED antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

产品形式:

Antigen affinity purified

存储溶液:

In 1X PBS, pH 7.4, with 0.09% sodium azide

产地:

美国