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折扣/货期| 货号：26416-1 mg | 规格：1 mg | 目录价：￥536 |
| 货号：26416-10 mg | 规格：10 mg | 目录价：￥3296 |
| 货号：26416-25 mg | 规格：25 mg | 目录价：￥5668 |
| 货号：26416-5 mg | 规格：5 mg | 目录价：￥1769 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Eganelisib
别名:
IPI-549
产品描述:
An inhibitor of PI3Kγ (IC50s = 16, 3,200, 3,500, and >8,400 nM for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively); selective for PI3Kγ over a panel of 468 mutant and nonmutant protein and lipid kinases and a panel of G protein-coupled receptors, ion channels, and transporters at 10 µM; inhibits migration of BMDMs (IC50 = 85 nM); sensitizes doxorubicin-resistant SW620/Ad300 cells to P-gp substrates, such as paclitaxel (IC50s = 710 and 6.7 nM for paclitaxel alone and in combination with IPI-549, respectively); enhances the tumor growth reduction of paclitaxel in an SW620/Ad300 mouse xenograft model at 3 mg/kg in combination with paclitaxel
保存温度:
-20
运输温度:
-20
预期分子量:
528.56428
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1693758-51-8
分子式:
C30H24N8O2
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