EIF6 Antibody / Eukaryotic Translation Initiation Factor 6-多抗-深圳欣博盛生物科技有限公司

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EIF6 Antibody / Eukaryotic Translation Initiation Factor 6

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31140

规格：100 ug

目录价：￥6488.05

产品详情

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产品名称:

EIF6 Antibody / Eukaryotic Translation Initiation Factor 6

产品描述:

EIF6 (Eukaryotic Translation Initiation Factor 6), also called ITGB4BP, is a human gene. By fluorescence in situ hybridization, Sanvito et al.(1998) mapped the gene to 20q11.2. Ceci et al.(2003) demonstrated that the ribosomal 60S subunit is activated by release of EIF6. In the cytoplasm, it is bound to free 60S but not to 80S subunits. Furthermore, the protein interacts in the cytoplasm with RACK1, a receptor for activated protein kinase C. Gandin et al.(2008) demonstrated that the protein is required for efficient initiation of translation in vivo. Null mouse embryos were lethal at preimplantation. Heterozygous mice had 50% reduction of EIF6 levels in all tissues, and showed reduced mass of hepatic and adipose tissues due to a lower number of cells and to impaired G1/S cell cycle progression.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P, IHC-F

同种型:

Rabbit IgG

免疫原:

An amino acid sequence from the middle region of human Eukaryotic Translation Initiation Factor 6 (QHIRNSLPDTVQIRR) was used as the immunogen for this EIF6 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the EIF6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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